2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methylthiazole-5-carboxylic acid pyridine solvate
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چکیده
In the title compound, C(16)H(16)N(2)O(3)S·C(5)H(5)N, the benzene and thia-zole rings of the Febuxostat [2-(3-cyano-4-isobut-yloxy)phenyl-4-methyl-5-thia-zolecarboxylic acid] mol-ecule are almost coplanar [dihedral angle = 2.4 (1)°]. The carboxyl group is coplanar with the thia-zole ring [O-C-C-C and O-C-C-S torsion angles of -0.7 (4) and 0.6 (3)°, respectively]. The pyridine mol-ecule of crystallization is linked to the Febuxostat mol-ecule through an O-H⋯N hydrogen bond. A weak π-π stacking inter-action is observed between the benzene ring of the Febuxostat mol-ecule and pyridine mol-ecule, with a centroid-centroid distance of 3.7530 (18) Å.
منابع مشابه
(5′′E)-1′′-Benzyl-1′-methyl-5′′-[4-(methylsulfanyl)benzylidene]-4′-[4-(methylsulfanyl)phenyl]dispiro[indoline-3,2′-pyrrolidine-3′,3′′-piperidine]-2,4′′-dione dichloromethane solvate
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